Mecanismo de resistencia antimicrobiana que presentan las cepas de s. aureus contra antibióticos b-lactámicos

Abstract

Staphylococcus aureus is a pathogenic bacterium that has developed bacterial resistance due to inappropriate use in administered treatments. This problem is global and continues to increase year after year. It is characterized by its ability to adapt well to different changes in its environment, causing infections both in the community and in hospitals. Objective: To analyze the mechanism of antimicrobial resistance presented by S. aureus strains against beta-lactam antibiotics through a literature review to understand the consequences of this global issue. Methods: This research is descriptive in nature and involves obtaining information from reliable bibliographic sources and scientific literature. Conclusion: The bacterial resistance of Staphylococcus aureus against beta-lactam antibiotics is a health problem. These virulent bacteria possess three mechanisms of resistance: production of beta-lactamases, modification of PBPs (penicillin-binding proteins), and resistance to methicillin. Key methods for detecting bacterial resistance include salt-mannitol agar, catalase test, coagulase test, antibiogram, and PCR.