Trasplante de microbiota fecal en los seres humanos

Abstract

Introduction: The intestinal microbiota carries out multiple essential functions that contribute to maintaining the stability of the human body; the current medical trend for treating diseases related to alterations in the intestinal microbiota is fecal microbiota transplantation, which involves transferring fecal material from a healthy donor into the patient's gastrointestinal tract. Objective: To identify the efficacy of fecal microbiota transplantation in the treatment of diseases related to alteration in the intestinal microbiota. Methods: The selection of high impact scientific articles from the last five years, predominantly categorized in quartiles I and II. For this purpose, specialized search engines such as PubMed, UpToDate and Google Scholar were used. Development: According to the research findings, this procedure has demonstrated its effectiveness and has benefited a large number of patients, especially in the treatment of recurrent Clostridioides difficile infection. However, favorable results have also been reported in the treatment of other gastrointestinal, metabolic, cardiovascular and neurodegenerative diseases, among others. Conclusions: This work reports a high level of safety of this procedure as a treatment for various pathologies associated with alterations in the intestinal microbiota, whose benefits impact an improvement in the quality of life of patients.