Efecto de Triamcinolona Acetonida en las Glándulas Adrenales usada para el control de Prurito en Dermatitis Alérgica por Picadura de Pulgas Canina.

Abstract

Allergic dermatitis due to flea bites (ADFB) is a cutaneous inflammatory disease in dogs, Glucocorticoids such as Triamcinolone Acetonida (TAC) are used to control pruritus. Potential side effects of these medications include alterations in the adrenal glands. The objective of this study was to determine the effect of Triamcinolone Acetonida on the adrenal glands used to control pruritus in allergic dermatitis due to canine flea bites in the city of Quito (Ecuador), as well as to determine measures of cranial and caudal pole width and length of the left and right adrenal glands. A prospective clinical study was carried out in 30 dogs with ADFB who were treated with TAC at a dose of 0.2 mg/kg subcutaneously as a single dose. Before treatment (day 0), at 15 and 30 days, the length and poles of both adrenals were measured by ultrasound. For DAPP we administer Serolaner at doses of 40 mg and 80 mg according to the weight of the patients. The findings indicated a significant reduction (p<0.05) in the size of the pole cranial y caudal left adrenal gland size at 15 days, we have partial recovery at day 30, however, it does not reach the size described on day 0. These results demonstrate the importance of monitoring adrenal function during glucocorticoid treatment.