Análisis sobre el manejo diagnóstico del lupus eritematoso sistémico cutáneo subagudo

Abstract

Introduction: Systemic lupus erythematosus (SLE) is an autoimmune disease of multifactorial etiology, characterized by the participation of different organs and systems and by presenting important immune disorders with autoantibodies. Objective: To update the guidelines on the diagnostic management of Systemic Erythematosus Lupus. Methods: Analysis of information obtained through biomedical research search engines, such as: PubMed, Google Scholar, Medscape and ScienceDirect; including a AUGE clinical practice guide. Results: Fifteen indexed articles were selected, together with a clinical practice guide, that fulfilled the established requirements and quality standards; in which epidemiological data, clinical characteristics and innovation in the diagnosis, treatment of SLE were investigated. Conclusions: Subcutaneous Cutaneous Erythematosus Lupus is diagnosed through the integration of symptoms, exploration findings, the results of complementary tests, mainly laboratory tests, and biopsy. Clinically, they are characterized by papulosquamous and annular lesions. It can be obtained by means of the serological mark, it shows positivity especially in anti-Ro and anti-La antibodies. We also have a skin biopsy in which it reveals histologically the participation of the dermis and the epidermis; The annular shape does not affect the cutaneous adnexa, unlike the psoriasiform variation.