Antimicrobial Assessment of Resins from Calophyllum Antillanum and Calophyllum lnophyllum.

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dc.contributor.authorCuesta Rubio, Osmany
dc.contributor.authorOubada, Alunad
dc.contributor.authorBello, Adonis
dc.contributor.authorMaes, Louis
dc.contributor.authorCos, Paul
dc.contributor.authorMonzote, Lianet
dc.date.accessioned2016-06-27T19:30:47Z
dc.date.available2016-06-27T19:30:47Z
dc.date.issued2015
dc.descriptionThe Calophyllum genus is well-known for its antimicrobial and cytotoxic activities, and therefore, we analyzed these biological activities for resins of Calophyllum antillanum and Calophyllum inophyllum growing in Cuba. C. antillanum resins sbowed a potent activity against Plasmodium falciparum (IC50 0.3 0.1 μg/mL), while its cytotoxicity against MRC-5 cells was much lower (IC50 2L6:t1.1 μglmL). In contrary, the resin of C. inophyllum sbowed an unspecific activity. The presence of apetalic acid, isoapetalic acid, calolongic acid, pinetoric acid pinetoric acid u, isocalolongic acid, pinetoric acid m, and isopinetoric acid m in c. antillanum resins was also confinned. These resuJts demonstrated for tbe first time tbe potential activity of C. antillanum resins against P.falciparum. Copyright© 2015 Jobo Wiley Sons, Ltd.es_ES
dc.format.extentpp. 1991.1994es_ES
dc.identifier.citationCuesta Rubio, O., Oubada, A., Bello, A., Maes., L., Cos, P., Monzote, L., (2015) Antimicrobial Assessment of Resins from Calophyllum Antillanum and Calophyllum lnophyllum. Phytother Res. 29 (12), p 1991-1994.es_ES
dc.identifier.issn0031-1820
dc.identifier.otherAC 001
dc.identifier.urihttp://repositorio.utmachala.edu.ec/handle/48000/5090
dc.language.isospaes_ES
dc.rightsopenAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/ec/es_ES
dc.subjectTRYPANOSOMAes_ES
dc.subjectPHYTOTHERAPY RESEARCHes_ES
dc.titleAntimicrobial Assessment of Resins from Calophyllum Antillanum and Calophyllum lnophyllum.es_ES
dc.typearticlees_ES

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