Anomalías cromosómicas producidas en los mecanismos de reparación del ADN

Abstract

DNA is the molecule responsible for storing the genetic information that encodes cellular functions, as it contains all the appropriate instructions for the molecule to replicate and survive, however it lives a constant struggle with the integrity of its genetic code, the constant damage to the DNA repair are the main alterations in DNA structure that can cause carcinogenic mutations and cell death. In addition, they complement the different endogenous and exogenous agents that can cause damage to the bases and alter the structure of the DNA molecule In the present investigation, the diseases produced by the DNA repair mechanisms are identified, through a bibliographic review in order to understand the biological importance in the mutations of the genetic material, as well as describe the failures in the repair mechanisms, in addition to relating the anomalies in DNA repair mechanisms.