Diseño de formulación y procedimiento para la elaboración de tabletas de furosemida con liberación prolongada.

Abstract

Furosemide is a compound that is highly effective in treatments for people with diuretic problems, it will act mainly on the ascending branch of the loop of Henle. The objective of this bibliographical work is the proposal to design a formulation and procedure for the preparation of programmed-release furosemide tablets. A non-experimental descriptive methodology was used, through the review of books and scientific articles it was possible to collect the necessary information that helped the investigation, this is how two types of formulations (wet method and direct compaction) are proposed, each with its respective process. processing, resulting in the best choice for the manufacture of prolonged release tablets is by wet method, since it complies with the proposal. Finally, it was possible to establish a design and procedure for the preparation of tablets that are effective and safe with the necessary excipients, complying with official regulations.