Efectos adversos autoinmunes post vacunacion covid-19

Abstract

Introduction: Vaccines against Covid-19 are currently in a Phase III of experimentation, generating controversies in the safety of being applied due to the appearance of rare autoimmune adverse effects, most reported after the administration of the second vaccination dose. Despite this, the "WHO" states that the benefits outweigh the risks in the population. Objective: To determine the autoimmune adverse effects that are being reported after the administration of the Covid-19 vaccines worldwide through the analysis of high-impact articles in order to capture the aforementioned effects in this research. Methodology: This is a descriptive study based on the compilation of scientific articles with the best evidence published in the last two years, obtained from metasearch engines such as: Pubmed and Elsevier. Conclusion: The autoimmune adverse effects that are known in the short and medium term are the majority produced by the Adenovirus vaccine (AztraZeneca), although the mRNA component vaccines also presented effects such as neurological diseases such as: Guillain Barré, Transverse Myelitis, Paralysis Bell's, Encephalopathy and rare cases of autoimmune pathologies such as: Subacute Thyroiditis, Immune Thrombocytopenia and autoimmune blistering diseases. With AztraZeneca, cases of Venous Thrombosis, Ischemic Cerebrovascular Accidents due to hypercoagulability disorder, Autoimmune Rheumatic Diseases including Vasculitis and SLE (Systemic Lupus Erythematosus), optic neuritis and autoimmune blistering diseases have been reported. All these effects are related to the theory of molecular mimicry produced after the administration of the vaccine.