Mecanismo de acción y farmacocinética de los antagonistas de angiotensina ii y atención farmacéutica en pacientes hipertensos

Abstract

Hypertension is a prevalent public health problem throughout the world, therefore, this work provides information on drug treatment and pharmaceutical care that help control this disease, aiming to determine the mechanism of action and pharmacokinetics of the Angiotensin II antagonists in hypertensive patients and their pharmaceutical care, to promote the rational use of drugs. The methodology used is of a qualitative approach, of a descriptive type, the documentary-bibliographic modality through the bibliographic review in scientific articles. Angiotensin II receptor antagonists are the first-line antihypertensives used for treatment, one of the drugs in this pharmacological group is losartan potassium, whose mechanism of action and pharmacokinetics help reduce arterial hypertension. In addition, a pharmaceutical care program for the hypertensive patient was developed, promoting the rational use of the drug and the regular practice of non-pharmacological treatment as an adjunct, necessary and important element for the control of the hypertensive patient through a healthy lifestyle.