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dc.contributor.authorCuesta Rubio, Osmany-
dc.date.accessioned2016-07-29T17:09:24Z-
dc.date.available2016-07-29T17:09:24Z-
dc.date.issued2015-
dc.identifierPhytotherapy Researches_ES
dc.identifier.citationCuesta Rubio, O. (2015) Antimicrobial Assessment of Resins from Calophyllum Antillanum and Calophyllum Inophyllum. Phytotherapy Research.es_ES
dc.identifier.issn10991573-
dc.identifier.otherAC 020-
dc.identifier.urihttp://repositorio.utmachala.edu.ec/handle/48000/6545-
dc.description.abstractThe Calophyllum genus is well-known for its antimicrobial and cytotoxic activities, and therefore, we analyzed these biological activities for resins of Calophyllum antillanum and Calophyllum inophyllum growing in Cuba. C. antillanum resins showed a potent activity against Plasmodium falciparum (IC50 = 0.3 ± 0.1 µg/mL), while its cytotoxicity against MRC-5 cells was much lower (IC50 = 21.6 ± 1.1 µg/mL). In contrary, the resin of C. inophyllum showed an unspecific activity. The presence of apetalic acid, isoapetalic acid, calolongic acid, pinetoric acid I, pinetoric acid II, isocalolongic acid, pinetoric acid III, and isopinetoric acid III in C. antillanum resins was also confirmed. These results demonstrated for the first time the potential activity of C. antillanum resins against P. falciparum. Copyright © 2015 John Wiley & Sons, Ltd.es_ES
dc.language.isoenges_ES
dc.publisherUnited Kingdomes_ES
dc.rightsopenAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/ec/es_ES
dc.subjectPHYTOTHERAPY RESEARCHes_ES
dc.subjectANTIMICROBIANOes_ES
dc.subjectINOPHYLLUM CALOPHYLLUMes_ES
dc.subjectPLASMODIUM FALCIPARUMes_ES
dc.titleAntimicrobial Assessment of Resins from Calophyllum Antillanum and Calophyllum Inophyllum.es_ES
dc.typearticlees_ES
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