Prevalencia del uso de antiinflamatorios no esteroideos en pacientes con diabetes mellitus tipo 2 atendidos en un centro de salud.

Abstract

Type 2 diabetes mellitus is a chronic disease that involves alterations in carbohydrate metabolism, caused by a deficiency in insulin secretion or action, which produces sustained hyperglycemia (Naranjo et al., 2021). This condition can cause progressive dysfunction in various organs (Jerez et al., 2022) and represents a major public health problem in the country due to its multiple complications, such as cardiovascular disease, kidney damage, and neuropathies, which significantly increase the risk of disability and mortality in the affected population. In addition to treatments aimed at glucose control, patients with type 2 diabetes commonly use nonsteroidal anti-inflammatory drugs (NSAIDs) to relieve pain and inflammation resulting from joint, musculoskeletal, or other related conditions. This study was descriptive, observational, cross-sectional, and non-experimental. A random sample of 365 patients with type 2 diabetes mellitus was obtained. A validated survey was used to measure the prevalence of NSAID use. The variables analyzed were type of NSAID, duration of use, frequency of use, and the development of adverse effects. Finally, the responses were classified and analyzed in a database created with Microsoft Office Excel software. The database was imported into Jamovi for processing and statistical analysis using the Mantel-Haenzel chi-square test. The results revealed that 91.78% of the patients surveyed (335 people) used NSAIDs. The most commonly used medications were paracetamol, ibuprofen, diclofenac, aspirin, and metamizole. The highest use was recorded among middle-aged adults (92.7%), with a slight predominance among men (92.5%). A positive association was found between the duration of NSAID use and the development of adverse effects, while no positive association could be established between the type of NSAID and the frequency of use.