Análisis invitro de pruebas cruzadas heterólogas entre sangre bovina y canina.

Abstract

"Cross-matching tests determine the serological compatibility between a blood donor and recipient in vitro. These procedures are crucial to avoid adverse reactions and increase the efficacy of transfusions. Although common since the 1950s, canine transfusions are not without risks, which justifies the use of compatibility tests to ensure safety. Transfusions treat severe conditions such as severe anemia and hemorrhages, but xenotransfusion, the transfusion between different species, faces challenges due to a lack of exhaustive studies. This research analyzed the in vitro compatibilities between bovine and canine blood, aiming to improve the safety of heterologous transfusions. The study included 115 dogs and bovine samples, following a rigorous cross-matching procedure to evaluate hemolysis and agglutination at different temperatures. The results showed an absence of hemolysis and variability in agglutination. Despite promising results, detailed studies evaluating the long-term risks and benefits of heterologous transfusions are still needed. We conclude that while cross-matching tests are essential for transfusion safety, further research is necessary to overcome current limitations and optimize the practice of xenotransfusion in veterinary medicine.