Métodos diagnósticos y tratamiento de artritis reumatoide

Abstract

Rheumatoid Arthritis (RA) is an inflammatory, chronic, progressive and degenerative pathology, autoimmune type, early arrest. If not treated in time, this disease can cause irreparable damage to the joints, causing inflammation of the synovial membrane, hyperplasia. and destruction of cartilage and bone. It also causes general alterations such as pulmonary, cardiovascular, locomotor, psychological and nervous system conditions. (1) The main and most frequent symptoms of this disease are chronic pain, stiffness, sensitivity, heat and joint swelling in one or both joints (whether in the hands or feet). (2) Over time, symptoms can worsen and spread to other joints, such as the elbows, shoulders, and knees, making it difficult to move around and perform everyday tasks such as writing, grasping objects with your hands, walking, and climbing stairs. (2) There is no apparent or specific cause of this disease, but there are different risk factors that can cause it, such as smoking, obesity and environmental pollution. (1) It is more common in women and older people are prone to contracting it. (4) Regarding laboratory tests, we found that the main diagnostic tests for RA are cyclic citrullinated antibodies (anti-CCP), which have greater specificity and sensitivity than the rheumatoid factor (RF) test and a mixture of both. It could be very useful for the early diagnosis of rheumatoid arthritis. (1)