Incidencia de síndrome de sjogren en pacientes que padecen lupus eritematoso sistémico

Abstract

Introduction: Systemic Lupus Erythematosus with Sjogren's Syndrome (SLE-SS) is a subgroup of patients with distinctive clinical and serologic features, although they share similarities with other subgroups. This type of lupus tends to increase with age and is characterized by a higher frequency of oral ulcers, anti-Ro and anti-La antibodies, and a lower incidence of renal disease and low C3 and C4 levels. The incidence of Sjogren's syndrome in SLE patients varies according to specific population groups and disease duration, with a worldwide prevalence of 14% to 17.8%. Dry eye and mouth symptoms are more common in patients with SLE-SS than in those without Sjogren's syndrome. Objective: To evaluate the incidence of Sjogren’s syndrome in patients with systemic lupus erythematosus by reviewing the literature updated in the last 5 years to improve diagnosis and comprehensive therapeutic management. Methodology: For the selection and development of the study, publications from the last 5 years from platforms such as Semantic Scholar and Pubmed with keywords of Descriptors in Health Sciences DeCS/MeSH were considered. Conclusion: The incidence of Sjogren's syndrome in patients with SLE has specific population groups such as blacks and Caucasians, appears in patients with long-standing disease and with a current worldwide prevalence of approximately 14% to 17.8%, among other current statistics, the incidence of SLE-sSS was present in 23.2% of patients.