Manejo diagnóstico y terapéutico actual del tumor carcinoide apendicular

Abstract

Introduction: the prevalence of malignant appendiceal neoplasms in statistical terms is relatively low, being 1 per 10,000 cases, with neuroendocrine tumors being the most frequent of all of them. The information on these tumors both in Latin America and in Ecuador is very limited, with few studies and reviews with few cases, so the main objective of this study is to summarize the existing information on appendiceal NETs through a review of global databases, and in this way, explain the clinical manifestations and thus be able to arrive at the most current therapeutic conduct.

Methods: Databases such as PubMed and LILACS were used to carry out an exhaustive review to update knowledge of appendiceal neuroendocrine tumors.

Results: According to their classification as functional, non-functional, localized or metastatic, according to the degree of mitotic division and the Ki-67 coefficient (%), a diagnostic plan can be established based on specialized imaging studies, laboratory tests that allow medics to reach the appropriate treatment, which depending on the size of the mass may be a candidate for a resection, if the NETs metastasize, then provide palliative treatment based on somatostatin analogues, hormonal inhibitors and monoclonal antibodies

Conclusion: the present study opens a range of possibilities for the diagnosis and treatment of an appendiceal NET as long as it is kept in mind that although its incidence is very low, its confusion with other pathologies is very common.