Enfermedad renal crónica: factores de riesgo y objetivos terapéuticos de las complicaciones cardiovasculares

Abstract

Cardiovascular complications are currently one of the main causes of morbidity and mortality in patients with chronic kidney disease, affecting about 80% of patients with stage 5 CKD. They occur as a result of a group of risk factors that develop due to alterations in the organs and systems secondary to loss of compensatory mechanisms, exogenous factors, progression of renal damage due to the reduction of glomerular filtration rate and proteinuria. The reduction of the different risk factors is key for the reduction of different complications, as well as the correct management of the different complications. OBJECTIVE: To analyze the risk factors and their therapeutic targets in the cardiovascular complications of chronic kidney disease by means of a systematic literature approach for the prevention and reduction of morbidity and mortality. MATERIALS AND METHODS: The information was collected through retrospective research of 25 scientific articles from quartile 1 and 2 journals 5 years old, obtained from the databases of the following digital platforms: UPTODATE, Pubmed and Elsevier. Google Scholar and Scielo. CONCLUSIONS: cardiovascular complications are the main cause of mortality in chronic kidney disease and every general practitioner should know their risk factors, for the reduction of morbidity and mortality of patients.