Antígeno de histocompatibilidad y hla-g y embarazo

Abstract

The ABO and Rh systems are of great clinical importance because they can establish that each person has a blood particularity, this difference can cause blood incompatibility if two people with different blood types interact. This can occur in organ transplants, grafts, and in pregnancy, because when a foreign body enters the body, the histocompatibility system is activated and works to recognize the foreign cells and eliminate them. This review study focuses on pregnancy where the case of a patient with Rh negative whose father is Rh positive giving in the product a blood incompatibility disorder that causes a hemolytic disease in the fetus is presented. It is known that the mother has a series of immunological mechanisms that act independently but when they come together they prevent the fetus from being rejected and can grow normally. Here, the HLA-G histocompatibility antigens in pregnancy are detailed. These HLA molecules produced by the major histocompatibility complex participate in the presentation of antigens to T lymphocytes and allow the activation of critical processes in the generation of the immune response1 through the interpretation of the mechanism of action against the immune response