Análisis de reacciones adversas a medicamentos en un paciente diabético y fumador severo con tratamiento farmacológico metformina y vareniclina

Abstract

Although medications are used to cure and prevent symptoms, they can trigger adverse reactions, which can be mild or serious. Among the types of adverse reactions we have type A and type B. Type A reactions occur when there is a high dose of the drug, this may be due to self-medication by the patient or a bad recommended dose. Some authors point out that they can also occur if the dose is adequate, it is one of the most common adverse reactions. Diabetic patients suffer from metabolic disorders that are identified by chronic hyperglycemia, due to the lack of insulin secretion, which is controlled by the drug metformin. Smoking triggers several preventable diseases, which can cause premature death, there are several treatments used for smoking cessation; Champix, Nicorette among others, each one acting differently by joining the receptors of the central and peripheral nervous system to fulfill the function of not having the need to smoke, likewise these can produce adverse reactions, due to their pharmacological action, or if treatment is abandoned before the recommended time. The purpose of this work is to analyze the adverse reactions to drugs such as Nicorette and Varenicline, define to which group of adverse reactions they belong and compare their mechanism of action in order to analyze the best option for smoking cessation; The present work was carried out through a descriptive investigation through review of scientific journals.