Patogenicidad de clostridium perfringens mediada por esporas bacterianas frente a infecciones humanas

Abstract

Clostridium perfringen is a spore-forming anaerobic rod-shaped bacterium with a wide environmental and even intestinal distribution that causes lethal diseases in animals and humans. Within the human clinic, C. perfringen type A and C are responsible for serious conditions due to the presence of alpha and beta toxins with a feeding and necrotizing effect on tissues capable of causing physiological and morphological risks, possibly causing death. Bacterial spores play a fundamental role in the survival of the bacteria because they provide protection for up to 20 years in unfavorable environments, which, when activated, releases toxicity to the different cells, causing damage to the pores of the cell membranes, allowing them to spread. become vulnerable due to the present permeability, resulting in clinical pathology. Objective: To describe the pathogenicity of Clostridium perfringens mediated by bacterial spores against human infections through bibliographic sources. Methods: Based on bibliographic research with a descriptive study, using the deductive method. Conclusion: the pathogenicity of Clostridium perfringens mediated by bacterial spores against human infections was described using bibliographic sources of high scientific impact.