Estudio de estabilidad de medicamentos dispensados en el mercado farmacéutico ecuatoriano

Abstract

Stability is the ability of a drug to retain its original properties for a defined time, which is why stability studies provide the community with certified information about the quality and useful life of a drug. In Ecuador there is an irrational use of medicines related to the lack of doctor-patient information, without knowing if the most used drugs are safe and stable. That is why, in the present research work, stability studies of the most widely sold drugs in the Ecuadorian pharmaceutical market were analyzed through the bibliographic review of national and international articles, in order to make a comparison and verify the quality and useful life. of the most used drugs. As results of the investigation, it was established that of the 8 articles that were consulted, medications such as omeprazole, sildenafil, fluoxetine, metronidazole, acetaminophen and ambroxol syrup did meet the required specifications, with the exception of amoxicillin, which none of their batches met the stability parameters. In this way, it is concluded that most of the medicines sold in Ecuador comply with the stability studies, guaranteeing their safety and useful life.