Mecanismos de drogorresistencia de la tuberculosis en la población infantil

Abstract

Tuberculosis is considered a pathology of great problem worldwide. Despite the strategies put in place by the World Health Organization, where there was evidence of a slight reduction in cases during 2015; however, for the year 2018 there was again an increase in these cases in the child population. It is considered that Ecuador ranks ninth in cases of tuberculosis in children in the Region of the Americas, and despite this position it is still considered a forgotten pathology and ignored by health systems, due to the lower number of cases unlike of adults and their low capacity to infect, since children are considered non- baciliferous. Methodology: This is a retrospective descriptive study, which is carried out through information from the main scientific databases such as PUBMED, SCIELO, GOOGLE ACADEMIC. Results: Around 15 scientific bibliographies were obtained in the main databases mentioned above, of great renown worldwide, which allowed the collection of essential information on the proposed topic. Conclusions: There are important mechanisms for drug resistance, mainly to the most powerful drugs used in the treatment of tuberculosis since ancient times. Added to this are certain risk factors and/or mechanisms of disease progression such as children with HIV, immunocompromised and malnourished.