Identificación de risperidona mediante cromatografía líquida de alta eficacia

Abstract

Risperidone belongs to the family of second-generation antipsychotics indicated in the treatment of some mental disorders such as schizophrenia, belonging to the group of essential drugs according to the World Health Organization. Through our investigative work, we show that according to our problem active principle, risperidone is the best instrumental technique for its identification according to its physical and chemical characteristics, in addition to directing ourselves by what is stated by the various pharmacopoeias, it turned out to be the reverse phase CLAE where the mobile phase must contain substances of polar nature polar as acetonitrile or methanol while the stationary phase carries a nonpolar C18 column. .As an objective we have to identify the most effective instrumental method through the physical and chemical characteristics of risperidone for its recognition and identification.