Efectos adversos y factores sociodemográficos para la no adherencia terapéutica al tratamiento con metotrexato en pacientes con artritis reumatoide

Abstract

Introduction: Rheumatoid arthritis is a disease of autoimmune origin that affects many people around the world, since there is no cure, there are medications that help improve the quality of life of the patient but that in turn cause adverse effects throughout the course of the disease. of your treatment,one of the cornerstones of treatment is methotrexate, which has been shown to be effective in relieving inflammatory symptoms and can be combined with biological drugs or corticosteroids depending on the criteria of the treating physician.Objective: To determine the adverse effects and sociodemographic factors that affect non-adherence to treatment with methotrexate, through a bibliographic review of scientific articles on the subject, for the education of patients with rheumatoid arthritis.Methodology: This descriptive bibliographical research was carried out qualitatively.Conclusion: The authors of the articles describe methotrexate as a drug that has several adverse reactions if there is not a correct use of it, either by combining it with folic acid or a greater consumption than necessary by the patient, that is why the correct adherence of the patient is of great importance,In addition, most emphasize that methotrexate is the cornerstone of treatment, whether combined with biological drugs or corticosteroids.