Estructura viral y variación genética como factores de riesgo para la infección del sars-cov2, causante del covid 19.

Abstract

The origin of a series of cases which met the criteria for pneumonia of unknown etiology was called COVID 19 infectious disease caused by SARSCoV-2 detected in Wuhan-China, later the virus spread worldwide causing a pandemic, the infection rate and mortality has been prevailing, one of the main causes is ignorance, being a pathology of variable epidemic behavior, for this reason the line of research aims to analyze the published studies with a focus on the structure and genetic variation to identify the risk factors and the affectation of them. Objective: To analyze the viral structure of COVID 19, its genetic variation as risk factors to determine the susceptibility in the development of the disease, the immune response and the severity of the symptoms by compiling scientific data that allows obtaining direct answers on the subject of study. Methodology: In this context, the analytical, descriptive method has been proposed, based on scientific articles, where the knowledge according to the research is based, which allows obtaining reliable information on the viral structure and genetic variation as risk factors in susceptibility to infection. of COVID 19. Conclusion: According to scientific evidence through various investigations, it is determined that genetics, as well as risk factors, play an important role in the appearance and development of SARS-CoV-2 infection as a consequence of difficulties in diagnosis, prognosis, alteration in symptoms plus increased mortality rate.