Método proteomico cómo nueva herramienta para el estudio del envejecimiento de las huellas dactilares en medicina forense

Abstract

ABSTRACT INTRODUCTION: The age of fingerprints is often raised in investigations and trials when suspects admit that they left their fingerprints at a crime scene, but claim that the contact occurred at a different time than the crime. The biomolecular components of fingerprint residues, such as amino acids, lipids, and proteins, can provide excellent means for determining the age of fingerprints; however, robust methodologies or detailed insights into molecular mechanisms over time are currently not available. Despite this, several promising studies have been presented, such as proteomics through mass spectrometry analysis. OBJECTIVE: To establish if the proteomic method is a relevant tool to study the aging of fingerprints in forensic medicine. METHOD: The review of scientific literature was carried out, in databases such as: EBSCO, SCIELO, PUBMED, COCHRANE, from September 2017 to the present. CONCLUSION: The proteomic method has successfully identified endogenous proteins and contaminants from donors that have been in contact with various body fluids. In addition, state-of-the-art proteomics was established as a sensitive tool for monitoring fingerprint aging, finding five proteins as promising candidates, which could be an important basis for further development of analytical protocols and fingerprint processing methods. data for age biomarker discovery and validation studies.