Importancia de biomarcadores en el diagnostico de hipertrigliceridemia en niños

Abstract

Dyslipidemia is a pathology that appears due to primary factors related to family history and external factors, in Ecuador they are part of the top ten causes of mortality and morbidity that affect children. This disease is closely related to the appearance of pathologies that affect the heart, for its diagnosis an evaluation of height and weight is made, which are complemented with the study of genetic factors where DNA tests are used that identify mutations in the activity of genes that start in the metabolism of lipids, in turn are complemented by the use of lipid biomarkers that better guide the recognition of metabolic diseases, and allow the selection of a pharmacological treatment based on the low consumption of saturated fats, with a balanced diet. To this end, a descriptive study was carried out based on the method of analysis in a pediatric patient, diagnosed with hypertriglyceridemia, allowing the following conclusions to be established: the use of biomarkers allows classifying and understanding the type of dyslipidemia that can occur in relation to primary genetic factors. and secondary or environmental and the use of ezetimibe in pharmacological treatment that significantly reduce cholesterol, increasing HDL cholesterol, and ciprofibrate that favors the reduction of triglycerides.