Helicobacter pylori y cáncer gástrico.

Abstract

Helicobacter pylori (H. pylori) is a microorganism associated with gastric cancer and premalignant lesions of the stomach. Research on this subject is carried out a large scale worldwide, which makes it necessary to constant-ly update this subject through bibliographic reviews of scientific articles. This is a descriptive, retrospective study, based on obtaining systematic do-cumentary information from research carried out in different parts of the world. Databases such as: PubMed, ScIELO, Science Direct and Scholar Goo-gle were used and articles from the last 5 years were selected. Thirty-five articles were included in the results. H. pylori has a higher incidence in coun-tries where gastric cancer is more frequent. Premalignant lesions appear after colonization of the microorganism years before the cancer occurs; the greater the morphological alteration found, the greater the probability of developing cancer. H. pylori infection is enhanced in the presence of genetic, environmental, dietary and socioeconomic factors of the population. Eradi-cation of this bacterium decreases the incidence of gastric cancer. It can therefore conclude that H. pylori is involved in the genesis of gastric cancer 23Helicobacter pylori y cáncer gástricoREVISTA CIENTÍFICAand its premalignant lesions. In countries where H. pylori has a higher inci-dence, the incidence of gastric cancer is also high. Definitive eradication of H. pylori from the gastric mucosa decreases both the incidence and mortality from gastric cancer.