Estudio de un caso clínico de falla hepática aguda fulminante asociado al virus de la Hepatitis B

Abstract

Fulminant acute liver failure (IHF) is a rare pathology characterized by impaired liver function in patients with no known prior liver disease, manifested with impaired liver enzymes, presence of coagulopathies, jaundice, and variable level of consciousness. According to the WHO, it indicates that approximately 30% of liver cirrhosis and up to 50% of hepatocarcinomas worldwide can develop into fulminant hepatitis. The objective of the following work was to analyze the biochemical alterations that occur in IHF caused by the hepatitis B virus (HBV). The methodology used consisted of a descriptive study of information gathering in scientific articles that allowed the resolution of the proposed clinical case. In conclusion, with the information obtained, it has been defined that biochemical markers such as: transaminases, bilirubins and prothrombin time are used to diagnose an IHF and also to know if any treatment designated for the patient is being effective, but these biomarkers have certain disadvantages and the main one is that they are usually altered by the administration of certain medications or other pathologies, it is for this reason that the detection of HBsAg is important as a key marker for the timely diagnosis of HBV infection.