Análisis de naproxeno y acetaminofén mediante cromatografía líquida de alta eficacia para su identificación y cuantificación

Abstract

Medications such as naproxen and acetaminophen are non-steroidal compounds and have very important therapeutic properties. In this work, the identification of naproxen as a contaminant in a batch of acetaminophen will be evaluated through the high efficiency liquid chromatography method coupled with spectrometry. as a detector for being an ideal method for contaminated compounds. For the quantification of acetaminophen, the high efficiency liquid chromatography method coupled to UV visible will be analyzed because it is appropriate in terms of the structure of the sample, that is, because it has a chromophore group, it will be easily absorbed by UV visible. For the choice of the methods, the physicochemical characteristics and advantages were taken into account, therefore, it is considered that they are linear, precise and exact methods.