Reacciones adversas y mecanismo de acción de antiinflamatorios no esteroides y esteroideos en pacientes asmáticos y con artritis reumatoide

Abstract

Adverse drug reactions refer to any undesirable and unintended response that occurs after the administration of a dose of a drug beyond its anticipated therapeutic effects. Rheumatoid arthritis is an inflammatory and degenerative autoimmune disease, which largely affects the female population. Asthma is a chronic condition in which the airways become inflamed causing shortness of breath, among other symptoms. Ibuprofen is an NSAID, which acts by inhibiting the cyclooxygenase enzyme and therefore has anti-inflammatory activity. The most common adverse reactions of NSAIDs in patients with a history of asthma and a diagnosi