Análisis de la presencia de drogas psicoactivas en muestras de cabello como biomarcador de consumo crónico en víctimas post mortem

Abstract

This present research work helps to determine the use of a biological sample that is not so common but very necessary when analyzing the cause of death of a Postmortem victim. Hair is a reliable sample at the time of the study, because it cannot be affected by the circumstances where the corpse is found or by changes in the body tissues during rigor. Based on the research data, the first hair applications date from 1858 to the present day, which led to the use of this test, due to its effectiveness of the long detection time, as well as the power of being able to establish a gradual profile of drug use. The objective of this project is to demonstrate the benefit of hair as a biomarker of chronic use in the toxicological diagnosis of psychoactive drug use in post-mortem victims. This work focuses on the study of various methods that can be applied to obtain information on psychoactive drugs found in post mortem victims, using biological samples such as hair, and thus determine the time span of consumption. The most decisive confirmation techniques that provide structural information on the most common drugs in our environment is mass spectrometry, in combination with a separation technique such as Gas Chromatography or Liquid Chromatography, it is currently the reference confirmatory technique used in the field.