Farmacovigilancia en pacientes diabéticos tipo 2 (dm2) que son atendidos en el hospital san vicente de paúl. pasaje. año 2018

Abstract

OBJECTIVE. The objective of this study was to establish pharmacovigilance in patients with type 2 diabetes mellitus which are treated at the San Vicente de Paul Hospital. This study is of prospective and observational cross section with a sample of 50 patients between men and women, evaluating the patient's condition, lifestyle, side effects and possible adverse reactions to the medications. METHODOLOGY. Through the application of surveys to patients, through a questionnaire of questions with their respective consent, data was collected, obtaining results that were used in the investigation. Diabetes mellitus, being one of the public health problems in Ecuador and the world, became the objective of study of this research, in order to provide the necessary help to improve the quality of life of the diabetic patient, taking into account account that diabetes mellitus can only be controlled until now, preventing the increase in mortality from this pathology. RESULTS We found that out of every 10 women, 2 male patients suffer from this pathology, therefore we can say statistically that 80% are women and 20% men, from these data we identify that 14% of patients do not have knowledge of the disease, while 86% if they have knowledge of the disease. It was identified within the population of 50 patients, that 6 of them had suspected adverse reactions (ADR) to the combination of metformin + glibenclamide, among which are tremors, headaches and nausea; while the remaining patients are asymptomatic. The responsible physicians were notified and the clinical files of the patients were reviewed to eliminate AMR suspicions and if their pharmacological treatment was adequate, once the medical records were examined, we detected that there were no suspicions of AMR in the files clinical It is suspected that the problem causing adverse effects to patients is due to improper storage as they tend to leave the drugs in places of the house exposing them to sunlight or moisture, this can directly affect the degradation of the active principle affecting the bioavailability of the drug. CONCLUSION. During the study we can verify that 88% of the patients are asymptomatic, while 12% presented adverse effects to the drug without suspicion of ADR, caused by inadequate storage of the medication and its mismanagement, ingesting it in alternate hours and not as prescribed by the doctor, because the prescriptions issued are written in illegible handwriting. At the end of this investigation, the implementation of a pharmaceutical care program is recommended to comply with the patient education phase regarding the correct administration of the medication, respecting the dosing time, the form and route of administration, in order to reduce suspicion of possible ADR in diabetic patients who are being treated at the San Vicente de Paúl Hospital in the City of Pasaje.