Pruebas diagnosticas complementarias para anemia hemolítica adquirida en pacientes adultos

Abstract

Introduction: Anemia represents a serious public health problem and is considered one of the most frequent diseases in humans, among which we have the syndrome of hemolytic anemia characterized by premature destruction of red blood cells before they reach their half-life of 120 days. Once the etiology of this disease is established, laboratory tests should be performed in a timely manner to confirm or rule out this disorder. Objective: Establish the efficacy of complementary examinations used in the diagnosis of hemolytic anemia acquired in adult patients Methods: In this work the documents used to carry out the research were updated scientific articles of higher quality and clinical hematology guidelines with no more than 5 years old, between systematic reviews and analytical studies. Results: We used 17 scientific articles, 2 clinical guides and 2 hematology books on the subject of hemolytic anemia, which provided us with the information necessary to carry out this project. Conclusions: Various studies are carried out for the diagnosis of this disease, of which we have hematic and biochemical biometrics. The direct Coombs test is still the basic test for the diagnosis of hemolysis. It also emphasizes the importance of other methods such as flow cytometry, radioimmunoassay (ELISA), SDS-PAGE, Eosin-5'-maleimide (EMA).