Diagnostico de la nefropatia mesangial por iga

Abstract

INTRODUCTION: nephropathy Mesangial IgA (IgAN), also known as Berger's disease has become in recent years a major medical problem have long-term prognosis uncertain and may lead the patient to CKD Terminal, reaching including dialysis and kidney transplant. OBJECTIVE: To establish the diagnosis of Mesangial Nephropathy due to IgA, through the review of scientific literature, for the effective management of this pathology. METHODOLOGY: A bibliographic search of Institutional Databases and databases of scientific information was carried out, taking into account in the present work articles published from 2015 to December 2018. CONCLUSIONS: For the diagnosis of IgA nephropathy Mesangial, should take into account the patient's clinical, such as hematuria, macroscopic and microscopic, in some cases acute renal failure and proteinuria. As for diagnostic methods, the Standard Gold for the diagnosis of Iga Nephropathy is the renal biopsy, which despite being an invasive method, gives us the certainty of the diagnosis and severity of it. There are also several biomarkers as urinary interleukin-6 / epidermal growth factor (EGF) / IL-6 serum IgA galactose, CD89, between serum and urine biomarkers that are associated with histological findings of gravity.