Parámetros bioquímicos en el diagnóstico del derrame pleural.

Abstract

In the diagnostic study of the pleural effusion, pleural fluid analysis should be considered, for this we have Light criteria and other biochemical parameters to differentiate pathologies that cause exudate and transudate. The objective is to establish, based on a descriptive review, the criteria and biochemical parameters for a correct diagnostic approach of the pleural effusion. Developing: Through a literature review of a descriptive type, we searched for articles in PUBMED, SCIENCEDIRECT and in high impact journals about the analysis of Light criteria and other biochemical parameters involved in the diagnosis of pleural effusion. It was determined that there are different biochemical parameters for the analysis of pleural fluid, serum exudates are determined albumin level to pleural fluid (LP) <1.2, proteins serious level to LP <3.1, cholesterol in LP> 60 mg / dl, LP ratio serum / serum> 0.3, pH <7.45, bilirubin LP / serum>, ADA level with a cut-off point> 35U for pulmonary tuberculosis (Tb), measurement of ceruloplasmin as another new parameter for exudate ≥13.34 mg / dl, with sensitivity and specificity of 89.7% and 83.3%, parapneumonic effusion with pH: <7.20, glucose: <60 mg / dL, LDH> 1000 U / l, C-reactive protein> 45 mg / dl. Conclusions: The diagnostic approach of the pleural effusion must be orderly, within the pleural fluid analysis we have other biochemical parameters in addition to the well-known criteria of light to differentiate between exudate and transudate.