Diagnóstico serológico de la hepatitis b

Abstract

Introduction: The Hepatitis B virus is a common pathogen that chronically infects and leads to complications such as cirrhosis, hepatocellular carcinoma and liver cancer. The fact of being very prevalent worldwide highlights its importance in the detection of its definitive diagnosis through the results of serological tests. The present publication was aimed at analyzing updated data on replication markers as a diagnostic method of Hepatitis B for a greater understanding of the disease and its different treatments. Development: 10 articles indexed from the last 5 years obtained through biomedical research search engines such as PubMed, Google Scholar, The New England Journal of Medicine, Medscape and ScienceDirect; including a clinical practice guide of the World Gastroenterology Organization, in which epidemiological data, clinical characteristics and innovation in the diagnosis, treatment and prevention of HBV were investigated. Conclusions: From the analyzed studies, it reveals various diagnostic findings after the arrest of the serological markers of the Hepatitis B virus, which concludes with greater clinical significance the HBsAg, HBcAg, HBeAg and its antibodies as the anti-HBs, the anti-core. , anti-core IG M, total anti core and the anti e; Its usefulness for the differentiation between an acute infection of a chronic infection was demonstrated, allowing later the realization of a greater vigilance in the epidemiological order and in the therapeutic behaviors to be executed.