Revisión de los fundamentos del abordaje terapeutico de la leucemia mieloide aguda en adultos en los ultimos dos años.

Abstract

Introduction: Acute myeloid leukemia (AML) is a malignancy that mostly affects males, with a mean age of approximately 67 years. In Ecuador, the incidence of the law proportionally to population growth. This disease progresses rapidly and is obtained by the inability to differentiate in mature blood cells, which causes an accumulation of malignant cells in the blood and bone marrow and after that in a multi-organ failure. The symptomatology has been reported thanks to clinical findings that groups of experts have reported during clinical practice. Patients with AML can achieve complete remission if they are at low risk and in the case of relapse or high risk treatment with a hematopoietic cell transplant is the choice. Objective: To describe the therapeutic management of acute myeloid leukemia (AML) based on the latest results to offer a useful review to general practitioners of medicine in Ecuador. Methodology: it was carried out through the revision of updated books, scientific articles, journals indexed in the Pubmed, Elsevier, Scielo and Google Scholar databases, related to the subject of study. Conclusions: The treatment of AML has progressed gradually during the last years, taking into account types of risks,where initial step or low risk stage treatment is only pharmacological treatment but in case of middle or high risk at pharmacological therapy it would be added haematopoietic cell transplantation.