Antimicrobial Assessment of Resins from Calophyllum Antillanum and Calophyllum lnophyllum.

Cuesta Rubio, Osmany; Oubada, Alunad; Bello, Adonis; Maes, Louis; Cos, Paul; Monzote, Lianet

DSpace Principal
→
Publicaciones
→
Scopus
→
Ver ítem

dc.contributor.author	Cuesta Rubio, Osmany
dc.contributor.author	Oubada, Alunad
dc.contributor.author	Bello, Adonis
dc.contributor.author	Maes, Louis
dc.contributor.author	Cos, Paul
dc.contributor.author	Monzote, Lianet
dc.date.accessioned	2016-06-27T19:30:47Z
dc.date.available	2016-06-27T19:30:47Z
dc.date.issued	2015
dc.identifier.citation	Cuesta Rubio, O., Oubada, A., Bello, A., Maes., L., Cos, P., Monzote, L., (2015) Antimicrobial Assessment of Resins from Calophyllum Antillanum and Calophyllum lnophyllum. Phytother Res. 29 (12), p 1991-1994.	es_ES
dc.identifier.issn	0031-1820
dc.identifier.other	AC 001
dc.identifier.uri	http://repositorio.utmachala.edu.ec/handle/48000/5090
dc.description	The Calophyllum genus is well-known for its antimicrobial and cytotoxic activities, and therefore, we analyzed these biological activities for resins of Calophyllum antillanum and Calophyllum inophyllum growing in Cuba. C. antillanum resins sbowed a potent activity against Plasmodium falciparum (IC50 0.3 0.1 μg/mL), while its cytotoxicity against MRC-5 cells was much lower (IC50 2L6:t1.1 μglmL). In contrary, the resin of C. inophyllum sbowed an unspecific activity. The presence of apetalic acid, isoapetalic acid, calolongic acid, pinetoric acid pinetoric acid u, isocalolongic acid, pinetoric acid m, and isopinetoric acid m in c. antillanum resins was also confinned. These resuJts demonstrated for tbe first time tbe potential activity of C. antillanum resins against P.falciparum. Copyright© 2015 Jobo Wiley Sons, Ltd.	es_ES
dc.format.extent	pp. 1991.1994	es_ES
dc.language.iso	spa	es_ES
dc.rights	openAccess	es_ES
dc.rights.uri	http://creativecommons.org/licenses/by-nc-sa/3.0/ec/	es_ES
dc.subject	TRYPANOSOMA	es_ES
dc.subject	PHYTOTHERAPY RESEARCH	es_ES
dc.title	Antimicrobial Assessment of Resins from Calophyllum Antillanum and Calophyllum lnophyllum.	es_ES
dc.type	article	es_ES